PRIME-CKD

Less pills, better pills
Personalized Drug Response:
Implementation and Evaluation in CKD

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About Prime-CKD

Chronic Kidney Disease (CKD) is one of the major causes of death in high income countries and its prevalence is growing rapidly. New therapies for the treatment of CKD have shown clear efficacy at a population level. Yet, individual patients respond differently with many patients showing suboptimal efficacy. This indicates that a ‘one size fits all’ approach is no longer sustainable. Currently there are no validated biomarkers (i.e. signal-substances that can be measured in blood or urine) in patients with CKD that aid in guiding optimal therapy for individual patients. Furthermore, there remains a large gap between biomarker research and actual implementation of biomarker based care in daily clinical practice.

“Individual and optimal treatment for every kidney patient; that is what we aim for.”

What is our objective?

The researchproject PRIME-CKD (Personalized drug Response: IMplementation and Evaluation in Chronic Kidney Desease) has a unique advantage to address the challenge we are facing as it builds on recent discoveries of new biomarkers to help guide optimal treatment to individual patients. The research must lead to new therapies for the treatment of CKD.

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Objective of Prime CKD

Latest News

PRIME-CKD Annual Stakeholder Meeting 2025

On 13 May 2025, the PRIME-CKD consortium organised a meeting for the consortium's stakeholders. Principal investigator Hiddo Lambers Heerspink and Stijn Gremmen presented the progress across the project’s work packages, highlighting developments in biomarker research and personalized treatment...
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PRIME-CKD PhD Students on the Road with Their Results

With results emerging across multiple work packages, our PRIME-CKD PhD students have been actively sharing their progress at national and international conferences. At the European Diabetic Nephrology Study Group meeting (Amsterdam, May 16–17), Erik Moedt and Andre de la Rambelje—both from Hiddo Lambers-Heerspink's ...
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Looking Back and Moving Forward – PRIME-CKD in Bologna

This year’s PRIME-CKD Annual Consortium Meeting took place in the beautiful city of Bologna. Over two inspiring days, we reflected on the past year’s progress across all work packages and looked ahead to the next steps in our shared mission. The event was filled with engaging discussions..
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