PRIME-CKD

Less pills, better pills
Personalized Drug Response:
Implementation and Evaluation in CKD

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About Prime-CKD

Chronic Kidney Disease (CKD) is one of the major causes of death in high income countries and its prevalence is growing rapidly. New therapies for the treatment of CKD have shown clear efficacy at a population level. Yet, individual patients respond differently with many patients showing suboptimal efficacy. This indicates that a ‘one size fits all’ approach is no longer sustainable. Currently there are no validated biomarkers (i.e. signal-substances that can be measured in blood or urine) in patients with CKD that aid in guiding optimal therapy for individual patients. Furthermore, there remains a large gap between biomarker research and actual implementation of biomarker based care in daily clinical practice.

“Individual and optimal treatment for every kidney patient; that is what we aim for.”

What is our objective?

The researchproject PRIME-CKD (Personalized drug Response: IMplementation and Evaluation in Chronic Kidney Desease) has a unique advantage to address the challenge we are facing as it builds on recent discoveries of new biomarkers to help guide optimal treatment to individual patients. The research must lead to new therapies for the treatment of CKD.

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Objective of Prime CKD

Latest News

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Looking Back and Moving Forward – PRIME-CKD in Bologna

This year’s PRIME-CKD Annual Consortium Meeting took place in the beautiful city of Bologna. Over two inspiring days, we reflected on the past year’s progress across all work packages and looked ahead to the next steps in our shared mission. The event was filled with engaging discussions..
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Bridging the Gap: From Biomarker Discovery to Precision Medicine Implementation in CKD

PRIME-CKD consortium leader Hiddo Heerspink gave an inspiring presentation during the 7th Annual CKD Drug Development Summit (Home - 7th CKD3 Summit) in Boston. Hiddo presented the large variations in both risk and response to guideline therapies for chronic...
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PRIME-CKD: Advancing Personalized Kidney Care on World Kidney Day

On World Kidney Day, the PRIME-CKD consortium is committed to raising awareness of the vital role kidneys play in our overall health and to reducing the prevalence and impact of kidney disease and related health issues worldwide. Through pioneering systems medicine research.....
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