About Prime-CKD

Chronic Kidney Disease (CKD) is one of the major causes of death in high income countries and its prevalence is growing rapidly. New therapies for the treatment of CKD have shown clear efficacy at a population level. Yet, individual patients respond differently with many patients showing suboptimal efficacy. This indicates that a ‘one size fits all’ approach is no longer sustainable. Currently there are no validated biomarkers (i.e. signal-substances that can be measured in blood or urine) in patients with CKD that aid in guiding optimal therapy for individual patients. Furthermore, there remains a large gap between biomarker research and actual implementation of biomarker based care in daily clinical practice.

“Individual and optimal treatment for every kidney patient; that is what we aim for.”

What is our objective?

The researchproject PRIME-CKD (Personalized drug Response: IMplementation and Evaluation in Chronic Kidney Desease) has a unique advantage to address the challenge we are facing as it builds on recent discoveries of new biomarkers to help guide optimal treatment to individual patients. The research must lead to new therapies for the treatment of CKD.

Objective of Prime CKD

Latest News

PRIME-CKD Publication: Urinary Clusterin identified as Biomarker for Kidney Disease Progression

The PRIME-CKD project reports new findings on the predictive value of urinary Clusterin (uCLU) for kidney disease progression and response to the Endothelin Receptor Antagonist Atrasentan in patients with type 2 diabetes and chronic kidney disease. In the SONAR trial it was found that atrasentan improves kidney outcomes...

Inclusion of patients for CKD-bioMatch personalized medicine trial started at University Medical Center Hamburg Eppendorf

Read quotes from researchers at the University Medical Center Hamburg Eppendorf about the recruitement of the first CKD-bioMatch patients in Hamburg, Germany. CKD-bioMatch aims to improve treatment for patients with progressive chronic kidney disease (CKD). CKD-bioMatch is now actively recruiting patients across Europe...

Lund University and Skåne University Hospital recruit first patients for CKD-bioMatch in Sweden

Read quotes from researchers at Lund University and Skåne University Hospital about the recruitement of the first CKD-bioMatch patients in Sweden. This trial aims to improve treatment for patients with progressive chronic kidney disease (CKD). CKD-bioMatch is now actively enrolling patient across Europe...

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